PEY1O: OXIDATIVE STRESS IN ADVANCED PRIMARY OPEN-ANGLE GLAUCOMA

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Oxidative stress in primary open-angle glaucoma.

PURPOSE To analyze oxidative stress in primary open-angle glaucoma (POAG). MATERIAL AND METHODS A case-control study including 90 eyes of 90 patients who needed antiglaucomatous surgery in the course of POAG (glaucoma group, n=50) and from patients who were operated of nonpathologic cataracts (cataract group, n=40). Free radical formation via lipid peroxidation by malondialdehyde-thiobarbitur...

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Oxidative Stress in Anterior Segment of Primary Open Angle Glaucoma

The glaucomas is a group of complex and heterogeneous ocular diseases representing the second leading cause of blindness, and almost 75 million people are affected worldwide (Quigley 1999) being a major issue for public health. The prevalence of glaucoma increases with age (Friedman et al. 2006). The reported prevalence among whites in their 80s varies widely across these studies, with estimate...

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Primary open-angle glaucoma

 Primary open-angle glaucoma (POAG) is an idiopathic disorder in which the resistance to outflow through the trabecular meshwork gradually increases and the intraocular pressure (IOP) rises, causing irreversible damage to the optic nerve  POAG is the second most common cause of vision loss in the U.S.  Usually asymptomatic until advanced visual field loss has occurred; less than 50% of those...

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Lactate dehydrogenase and oxidative stress activity in primary open-angle glaucoma aqueous humour.

Lactate dehydrogenase (LDH) and lactate are some of the hypoxy biochemical parameters. Extracellular activity of this enzyme increases under the condition of oxidative stress, since the cell integrity can be disrupted during the lipid peroxidation process. Subsequently that leads to the increase level of the lactic acid and lactic acid salts. The objective of this investigation is establishing ...

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[Options for correction of endothelial dysfunction and oxidative stress in patients with primary open-angle glaucoma].

OBJECTIVE To evaluate the efficacy of Tanakan in patients with primary open-angle glaucoma (POAG) with respect to its influence on vascular endothelial function and oxidative stress. MATERIAL AND METHODS Oxidative stress severity and antioxidant status were investigated in 52 patients with POAG divided into two groups. The effect of different treatment schemes on flow-dependent vasodilation a...

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ژورنال

عنوان ژورنال: Value in Health

سال: 2007

ISSN: 1098-3015

DOI: 10.1016/s1098-3015(10)65244-8